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The cytoprotective effect of BPC 157 against colonic ischemia/reperfusion-mediated mucosal damage is associated with the activation of the collateral circulation, which circumvents obstructed sites and results in the resolution of the obstruction, reduction of oxidative stress and normalization of NO synthesis

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SOD: copper-zinc SOD (Cu/Zn SOD), mainly present in the Graafian follicle and manganese SOD (MnSOD) concentrated mainly in the corpus luteum (124)