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In the model used to obtain the glutathione residuals, we also included the treatment factor as an explanatory term because the dependent variable was the target of the manipulation, inducing a direct and strong effect on its variability (Romero-Haro and Alonso-Alvarez 2015)

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Interestingly, Acod1-deficient mice are more susceptible to primary infection, but display enhanced T-cell-dependent protection upon secondary challenge with virulent F