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In the 26-week phase 2 trial, nausea affected 20% to 47% of participants across the 0.3–4.5 mg dose range, against 18% on placebo — the range widens with dose, which is why the trial escalated participants over up to six weeks before holding a target dose (Lau et al., 2021)

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Some athletes administer AOD 9604 60–90 minutes before training to layer lipolytic activity on top of training stimuli, but be sure to discuss this use case with your prescriber, as it isn’t the default protocol