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For further studies, we utilised Gpx4 flox/wt ;Villin-Cre +/− ( Gpx4 +/−IEC ) mice 27,28 , which specifically deleted one Gpx4 allele in the intestinal epithelium and resulted in a ~50% reduction of mRNA and protein levels in small and large intestinal IECs (Supplementary Fig

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Recent research suggests that neutrophils can be categorized into two subtypes: high-density neutrophils (HDNs) and low-density neutrophils (LDNs) [84]