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[DOI] [PubMed] [Google Scholar] 138.Mescka C.P., Guerreiro G., Hammerschmidt T., Faverzani J., de Moura Coelho D., Mandredini V., Wayhs C.A.Y., Wajner M., Dutra-Filho C.S., Vargas C.R

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In contrast, IRP2 is regulated through iron-dependent proteasomal degradation mediated by the E3 ubiquitin ligase FBXL5, which acts as a direct iron sensor through its hemerythrin domain [64]