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An FDA Reversal on Peptides Could Open the Market to Unsafe Drugs — ProPublica

Contraindications based on mechanism and theoretical concerns include active malignancy or cancer history (angiogenic properties may support tumor growth), pregnancy and lactation (insufficient safety data), cardiovascular disease requiring monitoring, and autoimmune disorders

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Serious side effects can include high blood pressure that may comprise symptoms like irregular heartbeats, chest pain, confusion, blurred vision, and severe headache