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Synthesis and characterization of the oxygen and desthio analogues of glutathione as… [PMID: 3985965] Laboratory literature summary: Synthesis and characterization of the oxygen and desthio analogues of glutathione as dead-end inhibitors of glutathione S-transferase

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Due to the large abundance of ROS in the mitochondria, antioxidants such as GPX4 plays a major role in protecting the mitochondria from oxidative damage