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Table of Contents Methodology of the Bayesian Framework Meta-Analysis Efficacy Thresholds of Amitriptyline Regimens Efficacy Metrics of Botulinum Toxin Type A Unpacking The Steal: Central Sensitization vs Peripheral Muscular Nociception Adherence Tradeoffs of Tricyclic Antidepressants Clinical Implications for Refractory Chronic Cephalalgia Closing Thoughts The management of chronic tension-type headache requires effective long-term strategies to reduce daily pain burdens