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They may involve thiol-disulfide exchange between protein thiol groups and GSSG, the conversion of protein thiol groups to thiyl radicals or sulfenic acids, or be mediated by GSNO (Dixon et al., 2005

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In another trial, 41 women with “mild to advanced photodamage” applied GHK-Cu eye cream for three months and saw reduced lines and wrinkles, improved skin density, and increased skin thickness better than both placebo and vitamin K cream.3 Similarly, in a pilot study investigating copper tripeptide topicals for aged skin, experts found that they increased skin thickness and elasticity, improved hydration, and boosted collagen synthesis.3 Hair growth In a review from 2023, experts explained that GHK-Cu may promote hair growth in a few different ways