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Reduced glutathione levels in the aqueous humor of NTG and POAG patients in the validation study Our above analysis indicated that glutathione levels gradually but clearly dropped with visual field loss

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Some need glucuronic acid (large, bulky tag), some need glutathione (for reactive electrophiles), some need a sulfate group (small, efficient for hormones and neurotransmitters), some need an acetyl group (for amines), some need a methyl group (for catecholamines and histamine), and some need an amino acid like glycine (for organic acids)