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The LR3 modification reduces IGF binding protein (IGFBP) affinity, extending the half-life to roughly 20 to 30 hours in animal studies, versus native IGF-1 at minutes to a few hours

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Commonly reported ones include: Pain, redness, or itching at the injection site Mild swelling Mild diarrhea Headache Less common effects that warrant a call to your provider include chest pain, shortness of breath, swelling in your feet or ankles, unusual fatigue, muscle weakness, vision changes, or trouble speaking