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A 2019 Cochrane review (Hong et al.) and the 2021 ASDS consensus paper both confirm what working injectors have known for fifteen years: HA filler is safe in trained hands, reversible with hyaluronidase, and produces durable correction lasting nine to eighteen months depending on product rheology and anatomical site

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Long-chain omega-3 fatty acid supplements in depressed heart failure patients: results of the OCEAN trial