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Beyond the direct role of macrophage in fibrin clot removal, macrophage and other phagocytes have also been shown to modulate thrombosis through the removal of active coagulation factors and activated platelets thus decreasing the ability for thrombus formation [96]

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It is widely researched in dermatological, hair follicle, and wound-healing models due to its influence on extracellular matrix regulation and growth factor expression

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