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[DOI] [PubMed] [Google Scholar] 7.Ferrigno A., Rizzo V., Bianchi A., Di Pasqua L.G., Berardo C., Richelmi P., Vairetti M

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These are two of the most rigorous and widely adopted methods in peptide manufacturing: SPPS enables precise, stepwise assembly of the amino acid sequence under tightly controlled conditions, while HPLC purification systematically removes synthesis byproducts and sequence variants to yield a high-purity final compound