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However, human clinical trials demonstrating sustained tissue accumulation and functional antioxidant benefit remain sparse, making real-world efficacy difficult to quantify

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Chen and colleagues reported that FMT from a plateau-specific species (plateau zokors) into low-altitude Sprague-Dawley rats effectively improved pulmonary metabolism, gene expression profiles, and respiratory function under hypoxic conditions, demonstrating significant potential of FMT for treating hypoxia-induced pulmonary hypertension ( Previous studies have demonstrated that acute cerebral ischemia can lead to gut microbiota dysbiosis, which in turn mediates neuroinflammatory responses through immune pathways (Singh et al., 2016)